Annuaire du laboratoire :

Vincent FAIVRE

Professeur MULTIPHASE
Site internet: Equipe 1-2 – multiphase
Photo de Vincent FAIVRE

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CV

In French Vincent Faivre est Professeur en Pharmacie Galénique à l’Université Paris-Sud (Université Paris-Saclay, France). Pharmacien diplômé de l’Université Lyon I, il a obtenu un doctorat de Technologie Pharmaceutique de l’Université Paris-Sud en 2000 puis son HDR en 2011. Après un premier poste d’enseignant-chercheur à l’Université Lyon I (2001-2004), il a rejoint l’équipe de Physiso-chimie des Systèmes Polyphasés de l’Institut Galien Paris-Sud. Ses travaux de recherche concernent principalement l’utilisation des matériaux lipidiques pour le développement de systèmes multi-échelles d’administration de principes actifs. Les corrélations entre les propriétés des matières premières, les paramètres critiques des procédés utilisés et les attributs des produits finis sont notamment considérées. Parmi d’autres, il a étudié des assemblages lipides-glycolipides pour le ciblage thérapeutique, des microsphères lipidiques obtenues par prilling et utilisées pour la libération contrôlée ou des nanoparticules Janus anisotropes potentiellement intéressantes pour la co-administration de principes actifs aux solubilités opposées.

In English Vincent Faivre is a Professor in Pharmaceutical Technology. He was graduated as a pharmacist from the University of Lyon I in 1998. He obtained his PhD in Pharmaceutical Technology from the University of Paris-Sud in 2000 and his HDR in 2011. After a position at Lyon I (2001-2004), he joined the Institut Galien Paris-Sud as a member of the team “physical chemistry of multiphase systems”. His work mainly deals with the used of lipid-based materials for the development of drug delivery systems, from bulk to nano-scales. The correlations between the raw materials properties (melting temperature, structural behavior, etc.), the process key-parameters and the final product attributes are notably investigated. Among others, he studied the surface modification of nanocarriers by glycolipids, lipid microspheres obtained by prilling and used for controlled drug delivery or patented Janus (anisotrope) nanoparticles that could be interesting to carry active pharmaceutical ingredients with opposite solubilities.

Mots clés

In French Matériaux lipidiques ; Assemblages supramoléculaires ; Propriétés thermotropes ; Homogénéisation haute-pression ; Diffraction des rayons x

In English Lipid-based materials ; Supramolecular assemblies; Thermotropic properties; High-pressure homogenization; x-ray diffraction

10 publications majeures

  • T. Truong-Cong, E. Millart, C.T.L. Le Tuyet, H. Amenitsch, G. Frebourg, S. Lesieur, V. Faivre – Scalable Process to produce Lipid-based Compartemented Janus nanoparticles with pharmaceutically approved excipients. Nanoscale, 10, 3654 – 3662, 2018.
  • A. Lambert, F. Bougrioua, O. Abbas, M. Courty, M. El Marssi, V. Faivre, S. Bresson – Temperature dependent Raman and x-ray diffraction studies of anhydrous milk fat. Food chemistry, 267, 187-195, 2018
  • K. Kemel, S. Tfaili, A. Tfayli, A. Baillet-Guffroy, V. Faivre, C. Laugel – ATR-FTIR Characterization of Janus Nanoparticles. Part I: Implementation of Spectroscopic Descriptors. J Pharm Sci., 107(9), 2457-2464, 2018
  • L.T.C Tran, C. Gueutin, G. Frebourg, C. Burucoa, V. Faivre – Erythromycin encapsulation in nanoemulsion based delivery systems for treatment of Helicobacter pylori infection: protection and synergy. Biochemical Biophysical Research Communications, 493(1), 146-151, 2017
  • P. Pivette, V. Faivre, J-B. Brubach, G. Daste, M. Ollivon, S. Lesieur -Polymorphism of glyceryl behenates: From the individual compounds to the pharmaceutical excipient. Chemistry and Physics of Lipids, 183, 191-203, 2014
  • L.T.C Tran, S. Lesieur, V. Faivre – Janus nanoparticles : materials, preparation and recent advances in drug delivery. Expert Opinion in Drug Delivery, 11(7), 1061-74, 2014.
  • F. Sequier, V. Faivre, G. Daste, M. Renouard, S. Lesieur. – Critical parameters involved in producing microspheres by prilling of molten lipids: From theoretical prediction of particle size to practice. European Journal of Pharmaceutics and Biopharmaceutics, 87(3), 530-540, 2014.
  • P. Pivette, V. Faivre, L. Mancini, C. Gueutin, G. Daste, M. Ollivon, S. Lesieur – Controlled release of a highly hydrophilic API from lipid microspheres obtained by prilling: Analysis of drug and water diffusion processes with X-ray-based methods. Journal of Controlled Release, 158(3), 393-402, 2012.
  • S. Bresson, D. Rousseau, S. Ghosh, M. El-Marssi, V. Faivre – Raman spectroscopy of the polymorphic forms and liquid state of cocoa butter. European Journal of Lipid Science and Technology, 113(8), 992-1004, 2011.
  • V. Faivre, P-L. Bardonnet, Boullanger, H. Amenitsch, M. Ollivon, F. Falson – Self-organization of synthetic cholesteryl oligoethyleneglycol glycosides in water. Langmuir, 25 (16), 9424-9431, 2009.
Catégories : Equipe 1-2 : MULTIPHASE
Mis à jour il y a 11 mois.

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